Financial challenge – uncertainty around funding 1 DescriptionResponseRationale Funding levels described in GHI (~$2.2 bn over 6 years) Maintain number of countries per original projections Continue research N/A Budget scenario Optimistic case Base case Funding remains at 2010 levels, with slow growth thereafter Reduce priority countries up to 5 by ‒ Accelerating graduation ‒ Discontinuing programs not yet taken to scale Delay entry into vaccine research Focuses resources on core activities and countries Preserves integrity of continuing programs 27 Pessimistic case Funding returns to 2008 levels, with slow growth thereafter Reduce priority countries up to 9 Reduce role in late-stage research Propose reduction to Global Drug Facility (legislated) Reduce involvement in Stop TB Partnership Programs protected as per base case Unlikely to achieve GHI treatment targets Lower case detection rates Less treatment success Impact on MDR
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