Vitamin C and Scurvy (II)
{"Image DocumentName": "Vitamin C and Scurvy (II)", "Image ImageDescription": "L-ascorbic acid plays a vital role in preventing prolyl 4-hydroxylase from being inactivated in a second reaction that it commonly catalyzes. In this reaction (see below), \uf061-ketoglutarate is oxidatively decarboxylated to succinate and CO2 in a reaction that does not involve hydroxylation of proline. In this reaction a critical Fe2+ metal ion of the enzyme is oxidized to the Fe3+ state, inactivating the enzyme for further catalysis. When L-ascorbic acid is present, the iron atom is reduced to the Fe2+ state, maintaining the active form of the enzyme.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}