Programmatic challenges: capacity and cost constraints of managing MDR-TB % treated of estimated cases of MDR-TB among all notified cases of TB Especially low in two regions with largest number of cases 2 29 Response Transition from project to program-based MDR-TB management Employ system-based approach consistent with USAID overall strength and experience Extend treatment beyond facility to community Help expand drug manufacturing capacity Issue Diagnosis of MDR TB will outpace capacity to treat, e.g., drug manufacturing capacity Capacity to manage/ensure the quality of rapid scale-up of MDR-TB treatment not yet clear
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