Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion C A Llewelyn, P E Hewitt, R S G Knight, K Amar, S Cousens, J Mackenzie, R G Will Findings 48 individuals were identified as having received a labile blood component from a total of 15 donors who later became vCJD cases and appeared on the surveillance units register.
{"Image DocumentName": "Possible transmission of variant Creutzfeldt-Jakob disease by", "Image ImageDescription": "THE LANCET \u2022 Vol 363 \u2022 February 7, Possible transmission of variant Creutzfeldt-Jakob disease by. blood transfusion. C A Llewelyn, P E Hewitt, R S G Knight, K Amar, S Cousens, J Mackenzie, R G Will. Findings 48 individuals were identified as having received a. labile blood component from a total of 15 donors who later. became vCJD cases and appeared on the surveillance unit\u2019s. register. One of these recipients was identified as developing. symptoms of vCJD 6\u00b75 years after receiving a transfusion of. red cells donated by an individual 3\u00b75 years before the donor. developed symptoms of vCJD. Interpretation Our findings raise the possibility that this. infection was transfusion transmitted. Infection in the. recipient could have been due to past dietary exposure to the. BSE agent. However, the age of the patient was well beyond. that of most vCJD cases, and the chance of observing a. case of vCJD in a recipient in the absence of transfusion. transmitted infection is about 1 in to 1 in", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}