Regulation of enzyme activity Allosteric enzymes use non-competitive inhibitors that bind to sites that activate or inhibit the enzyme –Binding of an activator to an allosteric site activates the enzyme –Binding of an inhibitor to an allosteric site inhibits the enzyme Another common method of control is through feedback inhibition ThreonineABCDisoleucine Enzyme 1Enzyme 2Enzyme 3Enzyme 4Enzyme 5 Feedback inhibition Initial substrate Endproduct and allosteric inhibitor of enzyme 1
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