Anesthetic Postconditioning
{"Image DocumentName": "Anesthetic Postconditioning", "Image ImageDescription": "Anesthetic preconditioning (APC) refers to the phenomenon whereby exposure of the heart to a volatile anesthetic before myocardial ischemia results in protection against the deleterious effects of myocardial ischemia and reperfusion. Compared with control conditions, this protection manifests as an improvement at the level of different variables such as infarct size and contractile function, but also coronary flow and free radical release at reperfusion. This type of protection strongly resembles ischemic preconditioning (IPC), which is a powerful endogenous protective mechanism that is present at different organ levels and occurs in various species. IPC refers to the phenomenon whereby a brief period of ischemia is able to protect the myocardium (ie, precondition) against the reversible and irreversible consequences of a subsequent longer period of ischemia, such as stunning, infarction, and the occurrence of arrhythmias. The mechanisms underlying IPC involve a complex system of intracellular signalling pathways, many of which are shared by APC. In addition, recent experimental data have indicated that APC is able to confer additional cardioprotection after IPC . Anesth Postconditioning: administration after reperfusion from ischemia, reuces reoxygenation injury.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}