Image: A small library of abietane-type diterpenoids amides was prepared from the plant-based dehydroabietylamine (left (1)) as a starting material, and the compounds evaluated for activity against Leishmania donovani and Trypanosoma cruzi. One compound (right (10)), an amide built from dehydroabietylamine and acrylic acid, was found to be highly effective against both parasites (Photo courtesy of Pirttimaa M et al., 2016, Journal of Natural Products).
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