Cryptococcus neoformans CAN infect healthy, non-immunocompromised hosts CAN infect healthy, non-immunocompromised hosts Today mainly associated with HIV-infected patients Today mainly associated with HIV-infected patients AIDS-defining illness AIDS-defining illness HAART has had an impact HAART has had an impact Mode of infection is inhalation but haematogenous Mode of infection is inhalation but haematogenous dissemination leads to meningitis dissemination leads to meningitis Diagnosis by direct microscopy or LPA antigen test Diagnosis by direct microscopy or LPA antigen test
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