Experimental overview Day 1 Estradiol and tumour cell implant Tumour growth Day 90 14 days Treatment Day 104 In vivo assay of stem cell activity in primary breast cancer xenografts after 14 days tamoxifen or vehicle control treatment Ciara O'Brien 1.Mammosphere assay 2.CD44/CD24/ESA cell sorting 3.Limiting dilution secondary transplants HARVEST TUMOUR FOR:
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