ATLANTIS The Alteplase Thrombolysis for Acute Non Interventional Therapy in Isquemic Stroke JAMA 1999; 282: 2019-2026 3 A 5 horas de evolución 140 centros de USA 547 pacientes 272 pacientes tratados con tPA Vs 275 con placebo TPA 0.9 mg/Kg The Alteplase Thrombolysis for Acute Non Interventional Therapy in Isquemic Stroke JAMA 1999; 282: 2019-2026 3 A 5 horas de evolución 140 centros de USA 547 pacientes 272 pacientes tratados con tPA Vs 275 con placebo TPA 0.9 mg/Kg
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