Oral bioavailability (F)  100% (imatinib), low (pazopanib:  15%) Food effect for pazopanib, nilotinib : –drug dissolution is increased with food –Re
{"Image DocumentName": "Oral bioavailability (F)", "Image ImageDescription": "\uf040 100% (imatinib), low (pazopanib: \uf040 15%) Food effect for pazopanib, nilotinib : drug dissolution is increased with food. Recommendation: fasted conditions in order to limit the intra-individual variability. A variability between drugs. And a food effect has been shown for some TKI. In the perpstive to perform a TDM for these drugs, it s particularly important to respect these recommandations.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}