Targeting FAK via RNAi enhanced the growth-inhibitory effects of <t>rapamycin.</t> a FAK protein ( i ) and mRNA expression ( ii ) in REH-empty vector and REH-FAK shRNA cells. b The <t>mTOR</t> inhibitor rapamycin and FAK down-regulation inhibited the proliferation of REH cells. REH-empty vector or REH-FAK shRNA cells were plated in 96-well plates and cultured with rapamycin (0–1000 nM). After 2 days ( i ) or 3 days ( ii ), the cells were treated with CCK-8 (10 μl/well) for 2 h and the absorbance was measured. The results represent the mean ± S.D. of three experiments performed in triplicate
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