Factors that Lead to Drug Resistance
{"Image DocumentName": "Factors that Lead to Drug Resistance", "Image ImageDescription": "ISTC Training Modules Healthcare provider-related factors: Inadequate initial treatment regimen: Wrong combination or doses, guideline noncompliance. Treatment in the dark for retreatment cases: no drug susceptibility testing available, or results delayed. Clinical errors: Adding a single drug to a failing regimen. Lack of proper monitoring. Lack of proper provider awareness. Healthcare provider-related factors may include: Inadequate regimen - this could happen if an inadequate regimen is prescribed (wrong combination or doses). The provider may not be aware of a drug-resistance pattern particularly if drug-susceptibility testing is not available or results are pending. Understanding and recognizing the risk factors that should raise suspicion for drug resistance is critical. Well-crafted local or national guidelines should be followed to optimize results. Poor case management and physician errors such as adding a single drug to a failing regimen may select for drug-resistant mutants. Lack of proper monitoring can delay appropriate interventions, allowing complications to go undetected and progress. A lack of knowledge regarding the complexities of TB treatment can lead to mismanagement and the development of drug resistance.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}