The Blood Blood Coagulation Blood Coagulation Coagulation is a natural mechanism that acts to diminish blood loss from hemorrhage Coagulation (thrombosis) especially in the microcirculation is also a manifestation of inflammation and sepsis Coagulation occurs in three Stages Platelet plug Platelet plug The cascade leading to fibrin (clot) formation The cascade leading to fibrin (clot) formation Clot retraction and repair (PDGF) Clot retraction and repair (PDGF)
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