Modulation of Pain Descending Pain Regulation:
{"Image DocumentName": "Modulation of Pain Descending Pain Regulation:", "Image ImageDescription": "Descending connections that modulate incoming pain impulses. Incoming painful stimuli are transmitted (A) to the dorsal horn, and from there (B) to the periaqueductal grey (PAG). Descending impulses pass (C) to the raphe nuclei, especially the nucleus raphe magnus, in the upper medulla, and thence back to the dorsal horn via reticulospinal fibres (D). The above shows only the serotonergic descending fibres. Other pain-suppressing impulses pass from the PAG to the locus coeruleus, and from there to the dorsal horn. Descending Pain Regulation: norepinephrine - alpha-2 stimulatory effects. serotonin. opiates relieve pain by stimulating mu and delta receptors at a host of sites.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}