Negative surface KK C1INH Activation of the intrinsic coagulation pathway KHPM pKK KK FXII FXIIa KHPM FXI - - - FXIa Bradykinin Arg 1 Pro 7 Ser 6 Phe 5 Gly 4 Pro 3 Pro 2 Phe 8 C Arg 9 Arg 1 Pro 7 Ser 6 Phe 5 Gly 4 Pro 3 Pro 2 Phe 8 C Des Arg 9 -BK Arg 1 Phe 7 Gln 6 Gln 5 Pro 4 Lys 3 Pro 2 Phe 8 C Gly 9 Leu 10 Met 11 Substance P APPACECPN NEPDPPIV
{}