NCBI Genome Resources RefSeq : Curation Review Sequence Editing Final Check Public Known Genes Gene Families Gene Clusters Identified Problems Sequence Database data Literature Correct errors Extend UTRs Splice Variants Annotate Features Quality Control Assignment Simple cases: 1-2 days Large gene families: months Time Reviewed Records: Human - 4,685 accessions (3,445 genes) Fly – 1,423 accessions (from FlyBase) Mouse,Rat – 45 accessions
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