Mechanism of action of β2-agonists
{"Image DocumentName": "Mechanism of action of \u03b22-agonists", "Image ImageDescription": "Extracellular. \u03b22R. \u03b22R. Gs. Gs. AC. Airway smooth muscle. Intracellular. cAMP. ATP. PKA (active) PK (inactive) Reference. Tashkin DP, Fabbri LM. Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents. Respir Res 2010; 11: 149. Relaxation. Stimulation of \u03b22-adrenoreceptors results in activation of adenylate cyclase, increased intracellular cAMP and subsequent airway smooth muscle relaxation. AC, adenylyl cyclase; ATP, adenosine triphosphate; \u03b22R, \u03b22 receptor; cAMP, cyclic AMP; Gs, stimulatory G protein; PKA, protein kinase A. Tashkin DP, Fabbri LM, Respir Res. 2010;11:149.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}