Orion Corporation Run1: The zero model This control stream came with the dataset, and likely originates from year 1982: $SUBROUTINES ADVAN2 KA=THETA(1)+ETA(1);absorption rate constant K=THETA(2)+ETA(2);elimination rate constant CL=THETA(3)*WT+ETA(3);clearance is scaled by weight SC=CL/K/WT;scaling of concentration observations is done ;by calculating V=CL/K and scaling by weight ;because dose is weight-adjusted.
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