www..uni-rostock.de Ulf Schmitz, Statistical methods for aiding alignment3 Expectation Maximization Algorithm an algorithm for locating similar sequence patterns in a set of sequences suspected parts are then aligned an expected scoring matrix representing the distribution of sequence characters in each column of the alignment will be generated the pattern is matched to each sequence and the scoring matrix values are then updated to maximize the alignment of the matrix to the sequences this procedure is repeated until there is no further improvement
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