Fluorine : significant dates 1886 Isolated by Henry Moissan (Nobel 1906) 1928 Freon® 12 (CF 2 Cl 2 ) 1938 Teflon® (PTFE) discovery of fluoropolymers 1954 Fried synthesise the 9-α-fluorohydrocortison fluorinated medicinal chemistry 1973 Discovery of ozon depletion by CFCs Rowland and Molina (Nobel 1995) 1987 Monteal Protocol Interdiction of synthesis and use of CFCs 1940s Development of fluorination methods
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