Transport Layer3-57 TCP Round Trip Time and Timeout Setting the timeout  EstimtedRTT plus safety margin  large variation in EstimatedRTT  larger safety margin r first estimate of how much SampleRTT deviates from EstimatedRTT: TimeoutInterval = EstimatedRTT + 4  DevRTT DevRTT = (1-  )  DevRTT +   |SampleRTT - EstimatedRTT| (typically,  = 0.25) Then set timeout interval:
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