Risk CategoryLDL-C Goal Initiate TLC Consider Drug Therapy High risk: CHD or CHD risk equivalents (10-year risk >20%) <100 mg/dL (optional goal: <70 mg/dL)  100 mg/dL  100 mg/dL (<100 mg/dL: consider drug Rx) Moderately high risk: 2+ risk factors (10-year risk 10% to 20%) <130 mg/dL (optimal <100 mg/dL)  130 mg/dL  130 mg/dL (100-129 mg/dL: consider Rx ) Moderate risk: 2+ risk factors (risk <10%) <130 mg/dL  130 mg/dL  160 mg/dL Lower risk: 0-1 risk factor <160 mg/dL  160 mg/dL  190 mg/dL Adapted from Grundy SM, et al.
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