The de Guise family From Lorraine (dukes of Lorraine), created Duke de Guise by Francis I His daughter married James V of Scotland: Mary, Queen of Scots, was their daughter  When she came to France as bride of Francis II, the family gained more prestige  Through her charm and love of the not-quite-all there, King Francis II, Mary wielded more and more influence through him  Her uncles, who had high positions in the French government (one was also a cardinal), gained great power in France They lead the Catholic League, organized opponents of the Huguenots in France
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