Survival of HCC patients after liver surgery according to subcellular CYLD expression.Kaplan-Meier analysis (N = 95) for overall survival (OS) of patients receiving liver resection, for the following subgroups: (nucCYLD+/cyt°CYLD−, nucCYLD+/cyt°CYLD+, nucCYLD−/cyt°CYLD+ and nucCYLD−/cyt°CYLD− (P = 0.06). Positive nuclear (nucCYLD+) and cytoplasmic (cyt°CYLD+) CYLD staining was defined as an immunohistochemical score (IHS) ≥3 for nucCYLD+ and ≥6 for cyt°CYLD+ (IHS ranging from 0 to 12, obtained by multiplication of the intensity and the quantity score).
{}