SUMMARY OF PRODUCT CHARACTERISTICS
{"Image DocumentName": "SUMMARY OF PRODUCT CHARACTERISTICS", "Image ImageDescription": "This is the SPC as approved for Austria, Belgium, Denmark, Finland, France, Germany, Ireland, Luxembourg, Netherlands, Portugal, Spain, Sweden, UK. For product use, please check the local SPC of the country you live in. 4.3 Contraindications. Hypersensitivity to the active substance or to any of the excipients. Additional contraindications in acute myocardial infarction, acute pulmonary embolism and acute ischaemic stroke: Actilyse is contraindicated in cases where there is a high risk of haemorrhage such as: significant bleeding disorder at present or within the past 6 months. known haemorrhagic diathesis. patients receiving oral anticoagulants, e.g. warfarin sodium. manifest or recent severe or dangerous bleeding. known history of or suspected intracranial haemorrhage. suspected subarachnoid haemorrhage or condition after subarachnoid haemorrhage from aneurysm. any history of central nervous system damage (i.e. neoplasm, aneurysm, intracranial or spinal surgery) recent (less than 10 days) traumatic external heart massage, obstetrical delivery, recent puncture of a non-compressible blood-vessel (e.g. subclavian or jugular vein puncture) severe uncontrolled arterial hypertension. bacterial endocarditis, pericarditis. acute pancreatitis. documented ulcerative gastrointestinal disease during the last 3 months, oesophageal varices, arterial-aneurysm, arterial/venous malformations. neoplasm with increased bleeding risk. severe liver disease, including hepatic failure, cirrhosis, portal hypertension (oesophageal varices) and active hepatitis. major surgery or significant trauma in past 3 months. Additional contraindications in acute myocardial infarction: any known history of haemorrhagic stroke or stroke of unknown origin. known history of ischaemic stroke or transient ischaemic attack (TIA) in the preceding 6 months, except current acute ischaemic stroke within 3 hours. Additional contraindications in acute pulmonary embolism:", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}