Atopic dermatitis is a serious condition that has been reported to affect between 30% and 50% of people who are HIV positive vs ≤20% of those who are HIV negative.2 The condition has been associated with elevated immunoglobulin E levels, eosinophilia, and possible Th1-Th2 imbalances.2,12 Because nearly all patients with AIDS demonstrate Th1-Th2 imbalances, they are at particularly high risk for atopic dermatitis.2 Patients generally present with chronic, red, thick, lichenified plaques and severe, incessant pruritus that can have an impact on daily function and sleep and reduce quality of life significantly.13 Isolated pruritic papules are sometimes observed. The hands, face, and eyelids, and areas of the body with large skin folds are most often affected; however, inflammatory flare-ups can affect the entire body and might necessitate hospitalization.13
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