Genome sequence of B. pseudomallei M. T. G. Holden., et al. PNAS 2004; 39 : 14240- 14245 Sigma N 1 in Chromosome 1 Sigma N 1 in Chromosome 1 : • Core
{"Image DocumentName": "Genome sequence of B. pseudomallei", "Image ImageDescription": "Sigma N 1 in Chromosome 1 : Core function as cell growth, metabolism, macromolecule. synthesis, cofactor, chemotaxis and motility. Sigma N 2 in Chromosome 2: Accessory functions as osmotic protection, regulation, secondary metabolism, adaptation and survival in different environments. The genome of B. pseudomallei K96243 has been described in detail: it is composed of two chromosomes. The larger size is common to all strains and thus represents the core genome that carries many genes associated with core functions such as cell growth and metabolism. In contrast, the smaller size is term the accessory genome.that carries more genes encoding accessory functions that could be associated with adaptation and survival in different environments. core genome. carries many genes associated with core functions such as cell growth and metabolism, accessory genome carries more genes encoding accessory functions that could be associated with adaptation and survival in different environments. Melioidosis is one of the emerging infectious diseases - part of our never-ending struggle to deal with bacteria that acquire new weapons to infect humans. For B. pseudomallei, the genome structure shows that both chromosomes have acquired whole new regions of DNA (genomic islands ), gaining new sets of genes to help the organism to live in humans and other environments. And, with double the amount of DNA in a typical bacterium, B. pseudomallei is one of the most adaptable. M. T. G. Holden., et al. PNAS 2004; 39:", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}