Gambogic acid (GA) inhibited tumor growth in a xenograft mouse model. The BALB/c nude mice were injected with U266 cells for some days followed by treatment with solvent or various doses of GA for 14 days. Then, the mice were killed, tumor removed and photographed (a). In addition, the tumor size (b), weight (c) and body weight (d) were measured. Bars are shown as mean ± SD (n = 6). The comparisons were made relative to untreated controls, and the different levels of significance were indicated as *P < 0.05 and **P < 0.01.
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