Parkinsonian disorders associated with dementia
{"Image DocumentName": "Parkinsonian disorders associated with dementia", "Image ImageDescription": "Parkinson\u2019s disease. Pathology of Lewy bodies (clumps of alpha-synuclein protien) in substantia nigra region of brain stem. 20% to 40% later develop dementia characterised by difficulties with abstract thought, memory, behavioural regulation and visual hallucinations. Dementia with Lewy bodies. Similar pathology to Parkinson\u2019s disease, but in addition plaques and tangles. A \u2018cross\u2019 between Parkinson\u2019s disease and Alzheimer\u2019s disease \u2013 cognitive features of Alzheimer\u2019s disease with movement disorder of Parkinson\u2019s disease (\u2018Parkinson\u2019s plus\u2019). Vivid visual hallucinations (faces, animals), rapid fluctuations of alertness, and falls are common. Attention is impaired more than memory. Copying shapes and understanding visual material is affected. Sensitive to antipsychotic medication, may respond to ACEIs. Progressive supranuclear palsy. Rigid Parkinson\u2019s disease, gaze palsy, swallowing problems and frontal dementia. Corticobasal degeneration (CBD) Rigidity, bradykinesia, apraxia (\u2018alien limb\u2019 syndrome), and behavioural variant of frontotemporal dementia.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}