Urogenital aging :effects on urogenital tract  Reduction in skin collagen content 1  Rectus fascia less elastic 2  Hydroxyproline content in connective tissue from women with stress incontinence 40% lower then continent controls 3  Estrogens have a direct effect on collagen synthesis 4  Changes in women with atrophy may be due to alteration in systemic collagenase activity 5  Urogenital prolapse associated with reduction in both vaginal and periurethral collagen 6 1 Brincat et al., 1985; 2 Landon et al., 1989; 3 Ulmstein et al., 1987; 4 Falconer et al., 1996; 5 Kushner et al., 1999; 6 Jackson et al., 1996; James et al., 1999
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