2010 Guidelines Reduction in Mortality with Anti-osteoporotic Medication Zoledronic acid has demonstrated a 28% relative reduction in mortality after hip fracture 128% relative reduction in mortality –Absolute risk reduction: 3.7% Meta-analysis has shown a 10% relative reduction in mortality with anti-osteoporosis therapies in older individuals at high risk of fracture 210% relative reduction in mortality –Absolute risk reduction: 0.4% 1.
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