Early or Moderate Stage Management of PD Level A – MAO-B inhibitors – selegiline, rasagiline Level A – MAO-B inhibitors – selegiline, rasagiline Level A – Dopamine agonists – pramipexole, ropinirole, rotigotine – caution in elderly, cognitive impairment, young males ( ) Level A – Dopamine agonists – pramipexole, ropinirole, rotigotine – caution in elderly, cognitive impairment, young males ( ) Level A - Carbidopa/levodopa – immediate release Level A - Carbidopa/levodopa – immediate release Level B - Carbidopa/levodopa – controlled release Level B - Carbidopa/levodopa – controlled release Recommended Years 1-5 (possibly more ) Questionable Co-enzyme Q10 Co-enzyme Q10 Amantadine Amantadine Therapeutic Agents Adjunctive Drug Therapy for Advanced PD Miyasaki, JM, et al., Neurology 2002;58:11–17 O.
{}