Mechanism of action of sorafenib
{"Image DocumentName": "Mechanism of action of sorafenib", "Image ImageDescription": "Sorafenib blocks receptor tyrosine kinase signalling (VEGFR, PDGFR, c-Kit and RET) and inhibits downstream Raf serine/threonine kinase activity to prevent tumour growth by anti-angiogenic, antiproliferative and/or pro-apoptotic effects. ERK, extracellular signal-regulated kinase; GDNF, glial-derived neurotrophic factor; MEK, mitogen-activated protein kinase kinase; PDGFR, platelet-derived growth factor receptor; SCF, stem cell factor; VEGFR, vascular endothelial growth factor receptor.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}